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Research suggests depression is a systemic disease affecting the entire body.

May 18

The results of a study conducted by an international team of researchers indicate depression is more than a mental disorder as it can be considered a systemic disease affecting our entire body. Results suggest that oxidative stress plays a role in depression and that antidepressant activity may be mediated via improving oxidative stress/antioxidant function.


This may explain co-morbidity between depression and a number of diseases including cardio-vascular disease and cancer, and why people suffering from depression die earlier. Additionally, it may focus research on finding new therapeutic targets for the prevention and treatment of depression.


Sara Jiménez-Fernández, Manuel Gurpegui, Francisco Díaz-Atienza, Lucía Pérez-Costillas, Miriam Gerstenberg, Christoph U. Correll. Oxidative Stress and Antioxidant Parameters in Patients With Major Depressive Disorder Compared to Healthy Controls Before and After Antidepressant Treatment. The Journal of Clinical Psychiatry, 2015; 1658 DOI: 10.4088/JCP.14r09179 


Full Article Link: http://www.psychiatrist.com/jcp/article/Pages/2015/v76n12/v76n1216.aspx

Dr. Sam Ozersky, MD

Sam is Mensante's founder and CEO. He speaks and writes extensively about the critical relationship between mental health and the workplace.